WDR77 polyclonal Antibody | BS8733

WDR77 polyclonal Antibody | BS8733 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: IHC,IF

Application Range: IHC 1:50 - 1:200 IF 1:50 - 1:200

Background: WDR77 is a component of the 20S PRMT5 (MIM 604045) -containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061) . This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: WDR77 polyclonal Antibody detects endogenous levels of WDR77 protein.

Molecular Weight: ~ 37kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Methylosome protein 50; MEP-50; Androgen receptor cofactor p44; WD repeat-containing protein 77; p44/Mep50; WDR77; MEP50; WD45; HKMT1069; Nbla10071

Immunogen: Recombinant full length Human WDR77.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: ESC Pluripotency and Differentiation Signaling Pathway,