Wilms Tumor Protein Polyclonal Antibody | BS65971

Wilms Tumor Protein Polyclonal Antibody | BS65971 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Sheep,

Application: IHC-P,FCM，

Application Range: IHC-P=1:100-500 Flow-Cyt=1ug/test

Background: Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Wilms Tumor Protein Polyclonal Antibody detects endogenous levels of Wilms Tumor Protein protein.

Molecular Weight: 55kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: WIT 2; WT 1; AWT1; FWT1; GUD; NPHS4; WAGR; Wilms tumor 1; Wilms Tumor; Wilms tumor protein; Wilms' tumor gene; Wilms' tumor protein; WIT2; WT; WT1; WT-1; WT1_HUMAN; WT33.

Immunogen: KLH conjugated synthetic peptide derived from human Wilms Tumor Protein:301-400/449

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: