Wnt-2, human recombinant | 7599

This protein belongs to the Wnt family of proteins. The WNT gene family consists of structurally related genes that encode secreted signaling proteins involved in the Wnt signaling pathway. Wnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt-2 is expressed in brain in the thalamus, in fetal and adult lung and in the placenta.

7599 | Wnt-2 human recombinant DataSheet

Biomolecule/Target: WNT2

Synonyms: INT1L1, IRP, Int-1-like protein 1, Int-1-related protein

Alternates names: TP53-induced glycolysis and apoptosis regulator (TIGAR)

Taglines: Plays a key role in regulating cellular growth and differentiation

NCBI Gene ID #: 57103

NCBI Gene Symbol: TIGAR

Gene Source: Human

Accession #: Q9NQ88

Recombinant: Yes

Source: E. Coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 31.6 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Phosphate, pH 7.5.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Amino acid sequence: ARFALTVVRH GETRFNKEKI IQGQGVDEPL SETGFKQAAA AGIFLNNVKF THAFSSDLMR TKQTMHGILE RSKFCKDMTV KYDSRLRERK YGVVEGKALS ELRAMAKAAR EECPVFTPPG GETLDQVKMR GIDFFEFLCQ LILKEADQKE QFSQGSPSNC LETSLAEIFP LGKNHSSKVN SDSGIPGLAA SVLVVSHGAY MRSLFDYFLT DLKCSLPATL SRSELMSVTP NTGMSLFIIN FEEGREVKPT VQCICMNLQD HLNGLTETRG GGYGRKKRRQ RRR