WNT1 Antibody (C-term) [APR32332G]

WNT1 Antibody (C-term) [APR32332G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This WNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-288 amino acids from the C-terminal region of human WNT1.

Cellular Localisation: Secreted, extracellular space, extracellular matrix. Secreted

Molecular Weight: 40982

Clone: Polyclonal

Gene Name: WNT1

Gene ID: 7471

Function: Ligand for members of the frizzled family of seven transmembrane receptors (Probable) . Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation (PubMed:23499309, PubMed:26902720, PubMed:28528193, PubMed:23656646) . In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling (By similarity) . Plays an essential role in the development of the embryonic brain and central nervous system (CNS) (By similarity) . Has a role in osteoblast function, bone development and bone homeostasis (PubMed:23499309, PubMed:23656646) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Synonyms: Proto-oncogene Wnt-1, Proto-oncogene Int-1 homolog, WNT1, INT1