WNT2 Antibody (Center) [APR33204G]

WNT2 Antibody (Center) [APR33204G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This WNT2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 254-287 amino acids from the Central region of human WNT2.

Cellular Localisation: Secreted, extracellular space, extracellular matrix. Secreted

Molecular Weight: 40418

Clone: Polyclonal

Gene Name: WNT2

Gene ID: 7472

Function: Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:20018874) . Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity) .

Summary: Tissue Location: Expressed in brain in the thalamus, in fetal and adult lung and in placenta.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Protein Wnt-2, Int-1-like protein 1, Int-1-related protein, IRP, WNT2, INT1L1, IRP