WNT4 Antibody [AMM02561G]

WNT4 Antibody [AMM02561G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H, M

Specificity: This WNT4 antibody is generated from a mouse immunized with a recombinant protein between 30-351 amino acids from human WNT4.

Cellular Localisation: Secreted, extracellular space, extracellular matrix

Molecular Weight: 39052

Clone: Monoclonal

Gene Name: WNT4

Gene ID: 54361

Function: Ligand for members of the frizzled family of seven transmembrane receptors (Probable) . Plays an important role in the embryonic development of the urogenital tract and the lung (PubMed:15317892, PubMed:16959810, PubMed:18179883, PubMed:18182450) . Required for normal mesenchyme to epithelium transition during embryonic kidney development. Required for the formation of early epithelial renal vesicles during kidney development (By similarity) . Required for normal formation of the Mullerian duct in females, and normal levels of oocytes in the ovaries (PubMed:15317892, PubMed:16959810, PubMed:18182450) . Required for normal down-regulation of 3 beta-hydroxysteroid dehydrogenase in the ovary (PubMed:15317892, PubMed:16959810, PubMed:18182450) . Required for normal lung development and for normal patterning of trachael cartilage rings (By similarity) .

Summary: N/A

Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:4000

Synonyms: Protein Wnt-4, WNT4