WYE-687 | B1730

WYE-687 is an ATP-competitive and selective inhibitor of mTOR with an IC50 value of 7 nM.

WYE-687 is an ATP-competitive and selective inhibitor of mTOR with an IC50 value of 7 nM.

B1730 | WYE-687 DataSheet

Alternate Name/Synonyms: WYE-687; WYE687 ; WYE 687 ; methyl N-[4-[4-morpholin-4-yl-1-[1-(pyridin-3-ylmethyl)piperidin-4-yl]pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]carbamate; N-[4-[4-(4-Morpholinyl)-1-[1-(3-pyridinylmethyl)-4-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]carbamic acid methyl ester

Appearance: Solid

Formulation: N/A

CAS Number: 1062161-90-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₈H₃₂N₈O₃

Molecular Weight: 528.61

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A ATP-competitive and selective inhibitor of mTOR

MDL Number: MFCD22417086

PubChem CID: 25229450

SMILES: COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCN(CC4)CC5=CN=CC=C5)C(=N2)N6CCOCC6

InChi: InChI=1S/C28H32N8O3/c1-38-28(37)31-22-6-4-21(5-7-22)25-32-26(35-13-15-39-16-14-35)24-18-30-36(27(24)33-25)23-8-11-34(12-9-23)19-20-3-2-10-29-17-20/h2-7,10,17-18,23H,8-9,11-16,19H2,1H3,(H,31,37)

InChi Key: VDOCQQKGPJENHJ-UHFFFAOYSA-N