XCL1/2 polyclonal Antibody | BS60985

XCL1/2 polyclonal Antibody | BS60985 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Lymphotactin is a chemokine-like molecule produced selectively, if not exclusively, by activated CD8+ T cells. Lymphotactin is a C-type member of the chemokine superfamily, but retains only the 2nd and 4th of the four cysteine residues conserved in other chemokines. In normal tissues, lymphotactin is expressed at high levels in spleen, thymus, small intestine, and peripheral blood leukocytes, as well as at low levels in lung, prostate, and ovary. Lymphotactin is chemotactic for CD4+ and CD8+ T cells but not for monocytes, and induces a rise in intracellular calcium in peripheral blood lymphocytes. The specific receptor for lymphotactin is XCR1, a member of the G protein-coupled receptor family. The gene which encodes lymphotactin maps to human chromosome 1q23.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: XCL1/2 polyclonal Antibody detects endogenous levels of XCL1/2 protein.

Molecular Weight: ~ 13 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Lymphotactin; ATAC; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; SCM-1-alpha; Small-inducible cytokine C1; XC chemokine ligand 1; XCL1; LTN; SCYC1; Cytokine SCM-1 beta; C motif chemokine 2; XC chemokine ligand 2; XCL2; SCYC2

Immunogen: A synthetic peptide corresponding to residues in Human XCL1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: