XL388 | B1733

XL388 is a potent and selective inhibitor of mTOR with IC50 value of 9.9 nM.

XL388 is a potent and selective inhibitor of mTOR with IC50 value of 9.9 nM.

B1733 | XL388 DataSheet

Alternate Name/Synonyms: XL388; XL 388; XL-388; [7-(6-aminopyridin-3-yl)-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]-(3-fluoro-2-methyl-4-methylsulfonylphenyl)methanone

Appearance: Solid

Formulation: N/A

CAS Number: 1251156-08-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₂₂FN₃O₄S

Molecular Weight: 455.5

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective inhibitor of mTOR

MDL Number: MFCD24386875

PubChem CID: 59604787

SMILES: CC1=C(C=CC(=C1F)S(=O)(=O)C)C(=O)N2CCOC3=C(C2)C=C(C=C3)C4=CN=C(C=C4)N

InChi: InChI=1S/C23H22FN3O4S/c1-14-18(5-7-20(22(14)24)32(2,29)30)23(28)27-9-10-31-19-6-3-15(11-17(19)13-27)16-4-8-21(25)26-12-16/h3-8,11-12H,9-10,13H2,1-2H3,(H2,25,26)

InChi Key: LNFBAYSBVQBKFR-UHFFFAOYSA-N