XPO1 polyclonal Antibody | BS70045

XPO1 polyclonal Antibody | BS70045 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB

Application Range: WB 1:500 - 1:2000

Background: The protein encoded by this gene mediates leucine-rich nuclear export signal (NES) -dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: XPO1 polyclonal Antibody detects endogenous levels of XPO1 protein.

Molecular Weight: ~ 123 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CRM1; Exportin-1; Exportin 1; Exportin1; Exp1

Immunogen: A synthetic peptide of human XPO1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Inhibition of Apoptosis,