YAP1 Antibody | 16-853

YAP1 Antibody | 16-853 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: A synthetic peptide of human YAP1.

Research Area: Cancer, Cell Cycle, Signal Transduction, Transcription

Tested Application: WB, IHC

Application: WB: 1:500 - 1:2000IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: DU145

Positive Control 2: HeLa

Positive Control 3: BT474

Positive Control 4: A-549

Positive Control 5: NIH/3T3

Positive Control 6: mouse brain

Molecular Weight: Observed: 75kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: YAP1, YAP, YAP2, YAP65, YKI

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.