YWHAB Antibody | 13-216

YWHAB Antibody | 13-216 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: A synthetic peptide of human YWHAB

Research Area: Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell

Tested Application: WB, IHC, IF

Application: WB: 1:500 - 1:1000
IHC: 1:50 - 1:100
IF: 1:20 - 1:50

Specificiy: N/A

Positive Control 1: Jurkat

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 31kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, pH7.3.

Concentration: N/A

Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.

Alternate Name: YWHAB, 14-3-3 alpha, 14-3-3 Beta, 14-3-3 protein beta/alpha, GW128, Protein 1054, HS1, KCIP-1, YWHAA

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.