YWHAZ Antibody [APR14004G]

YWHAZ Antibody [APR14004G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H, M, Rat

Specificity: This YWHAZ antibody is generated from a mouse immunized with a recombinant protein from human YWHAZ.

Cellular Localisation: Cytoplasm. Melanosome. Note=Located to stage I to stage IV melanosomes

Molecular Weight: 27745

Clone: Monoclonal

Gene Name: YWHAZ

Gene ID: 7534

Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation (PubMed:16959763) . In neurons, regulates spine maturation through the modulation of ARHGEF7 activity (By similarity) .

Summary: N/A

Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: 14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAZ