ZBTB10 Polyclonal Antibody | E-AB-53220

ZBTB10 Polyclonal Antibody | E-AB-53220 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: FLJ12752, OTTHUMP00000207119, RINZF, RINZFC, ZBT10, ZBTB10, Zinc finger and BTB domain containing protein 10, Zinc finger and BTB domain-containing protein 10, Zinc finger protein RIN ZF

Application: WB, ELISA

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling

Background: RINZF, also known as ZBTB10 (zinc finger and BTB domain containing protein 10), is a 847 amino acid protein that contains one BTB/POZ domain and two C2H2-type zinc fingers. Localized to the nucleus, RINZF is believed to play a role in transcriptional regulation. Specifically, RINZF is capable of binding to the CACC element of the Gastrin promoter. In this regard, RINZF competes with Sp1 for CACC binding and interferes with Sp1 transactivation, thereby regulating Gastrin gene expression. The rat RINZF protein shares 98% homology with the human RINZF protein, suggesting that RINZF is a conserved protein. Due to alternative splicing events, two RINZF isoforms exist. In addition, RINZF may be phosphorylated by ATR or ATM upon DNA damage.

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human ZBTB10

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:2000-1:5000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 95 kDa

Molecular Weight(Observed): Refer to figures