ZC3H12C Antibody | 5677

ZC3H12C Antibody | 5677 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: ZC3H12C antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZC3H12C.
The immunogen is located within the first 50 amino acids of ZC3H12C.

Research Area: Innate Immunity

Tested Application: E, WB, IHC-P, IF

Application: ZC3H12C antibody can be used for detection of ZC3H12C by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1463 - Rat Brain Tissue Lysate

Positive Control 2: Cat. No. 10-301 - Human Brain Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: ZC3H12C Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: ZC3H12C Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: ZC3H12C antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: ZC3H12C Antibody: MCPIP3, KIAA1726, MCPIP3, Probable ribonuclease ZC3H12C, MCP-induced protein 3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: ZC3H12C Antibody: ZC3H12C, also known as MCPIP3, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. Similar to ZC3H12A, ZC3H12C expression in macrophages is highly increased after treatment with lipopolysaccharide (LPS) , suggesting it also may play a role in host immunity and inflammatory response.