ZC3H12D Antibody | 5679

ZC3H12D Antibody | 5679 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: ZC3H12D antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZC3H12D.
The immunogen is located within amino acids 280 - 330 of ZC3H12D.

Research Area: Innate Immunity

Tested Application: E, WB

Application: ZC3H12D antibody can be used for detection of ZC3H12D by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1306 - Human Spleen Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 58 kDa
Observed: 57 kDa

Validation: N/A

Isoform: N/A

Purification: ZC3H12D Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: ZC3H12D Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: ZC3H12D antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: ZC3H12D Antibody: TFL, p34, MCPIP4, C6orf95, dJ281H8.1, TFL, Probable ribonuclease ZC3H12D, MCP-induced protein 4

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: ZC3H12D Antibody: ZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages is also increased after treatment with lipopolysaccharide (LPS) , although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it also may play a different role in host immunity and inflammatory response.