ZFPM2 Antibody (C-term) [APR14030G]

ZFPM2 Antibody (C-term) [APR14030G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ZFPM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 883-911 amino acids from the C-terminal region of human ZFPM2.

Cellular Localisation: Nucleus.

Molecular Weight: 128159

Clone: Polyclonal

Gene Name: ZFPM2

Gene ID: 23414

Function: Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential during cardiogenesis. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. Also required in gonadal differentiation, possibly be regulating expression of SRY. Probably acts a corepressor of NR2F2 (By similarity) .

Summary: Tissue Location: Widely expressed at low level.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Zinc finger protein ZFPM2, Friend of GATA protein 2, FOG-2, Friend of GATA 2, hFOG-2, Zinc finger protein 89B, Zinc finger protein multitype 2, ZFPM2, FOG2, ZNF89B