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ZFR Polyclonal Antibody | BS65831

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BW-BS65831
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Description

ZFR Polyclonal Antibody | BS65831 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,

Application: WB,

Application Range: WB=1:500-2000

Background: ZFR is 1,074 amino acid RNA-binding protein. In human, ZFR is expressed in lung, liver, lymphocytes, heart, pancreas, kidney and placenta, and regulates postimplantation and gastrulation stages of development. Murine ZFR is observed in testis, ovary and brain. With elevated levels of expression during meiosis, ZFR associates with chromosome foci in meiotic cells. ZFR contains 1 DZF domain and localizes in the somatodendritic compartment of hippocampal neurons and colocalizes with STAU2 in cytosolic RNA granules. Knockout of ZFR in mouse embryo prevents the development of some embryonic structures leads to an increase in programmed cell death with a decrease in mitotic index.

Storage & Stability: Store at 4°C short term. Aliquot and store at -4°C long term. Avoid freeze-thaw cycles.

Specificity: ZFR Polyclonal Antibody detects endogenous levels of ZFR protein.

Molecular Weight: ~117kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: FLJ41312; hZFR; M phase phosphoprotein homolog; M-phase phosphoprotein homolog; zfr; ZFR_HUMAN; zinc finger RNA binding protein; Zinc finger RNA-binding protein.

Immunogen: KLH conjugated synthetic peptide derived from human ZFR:271-370/1074

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway:

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