ZIMP7 Antibody | 6235

ZIMP7 Antibody | 6235 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: ZIMP7 antibody was raised against a 17 amino acid synthetic peptide near the center of human ZIMP7.
The immunogen is located within amino acids 270 - 320 of ZIMP7.

Research Area: Signal Transduction

Tested Application: E, WB

Application: ZIMP7 antibody can be used for detection of ZIMP7 by Western blot at 0.25 - 0.5 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Specificiy: At least four isoforms are known to exist. ZIMP7 antibody is predicted to not cross-react with other PIAS protein family members.

Positive Control 1: Cat. No. 1288 - A20 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: ZIMP7 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: ZIMP7 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: ZIMP7 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: ZIMP7 Antibody: NET27, ZIMP7, hZIMP7, TRAFIP20, KIAA1886, HRIHFB2007, Zinc finger MIZ domain-containing protein 2, PIAS-like protein Zimp7

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: ZIMP7 Antibody: ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription) -like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR) - mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.