ZMYND8 polyclonal Antibody | BS61552

ZMYND8 polyclonal Antibody | BS61552 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. Receptor for activated C kinases, termed RACKs, are intracellular receptors for activated PKC that serve as anchors and may be involved in the activation-induced translocation of PKC. RACK7 (receptor for activated C kinase 7), also known as ZMYND8 (zinc finger MYND domain-containing protein 8), PRKCBP1 (protein kinase C (PKC) -binding protein 1) or PRO2893, is a widely expressed protein with predominant expression in pancreas, lung, placenta and brain. RACK7 contains one bromodomain, one PHD-type zinc finger, one MYND-type zinc finger and one PWWP domain. Via its C-terminus, RACK7 interacts with PKC ∫ and is believed to play a role in PKC signaling and function as a transcription regulator. In response to DNA damage, RACK7 is phosphorylated by ATM or ATR. In addition, multiple isoforms exist for RACK7.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ZMYND8 polyclonal Antibody detects endogenous levels of ZMYND8 protein.

Molecular Weight: ~ 190 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Protein kinase C-binding protein 1; Cutaneous T-cell lymphoma-associated antigen se14-3; Rack7; Zinc finger MYND domain-containing protein 8

Immunogen: Synthetic peptide, corresponding to amino acids 586-630 of Human ZMYND8

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Pathway: