ZXX2-77 | B2937

ZXX2-77 is a benzenesulfonanilide derivative that inhibits cyclooxygenase-1 (COX-1) with an IC₅₀ of 3.2 μM. It shows more potent analgesic activity than aspirin at 30 mg/kg by po. It can be used as a lead compound to develop better COX-1 inhibitors as analgesic agents without gastric disturbance.

ZXX2-77 is a benzenesulfonanilide derivative that inhibits cyclooxygenase-1 (COX-1) with an IC₅₀ of 3.2 μM. It shows more potent analgesic activity than aspirin at 30 mg/kg by po. It can be used as a lead compound to develop better COX-1 inhibitors as analgesic agents without gastric disturbance.

B2937 | ZXX2-77 DataSheet

Alternate Name/Synonyms: 4-Amino-N-(4-chlorophenyl)-N-methyl-benzenesulfonamide; N-(4-Chlorophenyl)-N-methyl-4-aminobenzenesulfonamide; 4-Amino-4'-chloro-N-methylbenzenesulfonanilide; COX-1 Inhibitor II

Appearance: Solid

Formulation:

CAS Number: 304913-22-2

Structure Available?: True

Peptide sequence:

Salt Form: false

Molecular Formula: C₁₃H₁₃ClN₂O₂S

Molecular Weight: 296.77

Cell-Permeable?: True

Purity: 97%

Solubilities: Soluble in in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An inhibitor of COX-1

MDL Number:

PubChem CID: 16126699

SMILES: CN(C1=CC=C(C=C1)Cl)S(=O)(=O)C2=CC=C(C=C2)N

InChi: InChI=1S/C13H13ClN2O2S/c1-16(12-6-2-10(14)3-7-12)19(17,18)13-8-4-11(15)5-9-13/h2-9H,15H2,1H3

InChi Key: AFQPTMJHMKDDIB-UHFFFAOYSA-N