1-Azakenpaullone | 1944

Cell-permeable. A Potent and ATP-competitive GSK-3β (glycogen synthase kinase-3β) inhibitor (IC₅₀ = 18 nM).

1-Azakenpaullone is a potent and ATP-competitive GSK-3β (glycogen synthase kinase-3β) inhibitor (IC₅₀ = 18 nM).

1944 | 1-Azakenpaullone DataSheet

Alternate Name/Synonyms: 9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one

Appearance: Off-white to tan solid

Formulation: N/A

CAS Number: 676596-65-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₀BrN₃O

Molecular Weight: 328.16

Cell-Permeable?: Yes

Purity: ≥98% by NMR

Solubilities: DMSO (~ 100 mg/ml)

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A potent GSK-3β inhibitor

MDL Number: MFCD09037522

PubChem CID: 6538897

SMILES: C1C2=C(C3=C(C=CC=N3)NC1=O)NC4=C2C=C(C=C4)Br

InChi: InChI=1S/C15H10BrN3O/c16-8-3-4-11-9(6-8)10-7-13(20)18-12-2-1-5-17-15(12) 14(10)19-11/h1-6,19H,7H2,(H,18,20)

InChi Key: NTSBZVCEIVPKBJ-UHFFFAOYSA-N