Description
2-Deoxy-2-fluoro-L-fucose | MD06089
Can be metabolised inside the cell to a substrate-based inhibitor of fucosyltransferases. It can also be converted to GDP-2-deoxy-2-fluoro- L-fucose, a competitive inhibitor of α-1,3-fucosyltransferase. Reduces fucosylation of IgG in antibodies, which increases therapeutic efficacies of antibodies that cause antibody-dependent cellular cytotoxicity.
Additional Information
M. F.: |
C6H11FO4 |
M. W.: |
166.15 g/mol |
Color: |
white to off-white |
Form: |
powder |
Purity (HPLC): |
min. 98.0 area-% |
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