2-Methoxyestradiol | 2166

2-Methoxyestradiol (2-ME) is major estradiol metabolite that acts as a potent inhibitor of endothelial cell proliferation and angiogenesis. It displays little affinity for classical estrogen receptors.

2-Methoxyestradiol (2-ME) is major estradiol metabolite that acts as a potent inhibitor of endothelial cell proliferation and angiogenesis. It displays little affinity for classical estrogen receptors.

2166 | 2-Methoxyestradiol DataSheet

Alternate Name/Synonyms: 2-​methoxy-​estra-​1,​3,​5(10)-​triene-​3,​17β-​diol; 2-Hydroxyestradiol 2-methyl ether; NSC659853; 2-ME2; Panzem

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 362-07-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₂₆O₃

Molecular Weight: 302.41

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO (10 mg/ml) or EtOH (10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An angiogenesis inhibitor

MDL Number: MFCD00010489

PubChem CID: 16760554

SMILES: CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)OC)O

InChi: InChI=1S/C19H26O3/c1-19-8-7-12-13(15(19)5-6-18(19)21)4-3-11-9-16(20)17(22-2)10-14(11)12/h9-10,12-13,15,18,20-21H,3-8H2,1-2H3/t12?,13?,15?,18-,19-/m0/s1

InChi Key: CQOQDQWUFQDJMK-WRWXEFHESA-N