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3943 | C/EBP alpha Antibody DataSheet

3943BP | C/EBP-alpha Blocking Peptide DataSheetAntibody Target: C/EBP-alphaAccession #: NP_036656.1Gene ID: 24252Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

A1113 | C1 Esterase Inhibitor Antibody DataSheet

A single chain glycoprotein which inhibits C1, C1r, C1s, plasma kallikrein, Factors XIa. XIIa, and plasmin. Present in plasma at 16-33 mg per 100 ml. C1 esterase inhibitor deficiency is a rare...

C1 Inhibitor is a member of the serpin family of structurally related proteins, and is the primary regulator of the immune complement system. C1 Inhibitor is a protease inhibitor that functions to...

C12 Galactosylceramide (d18:1/12:0) | B3375Description: C12 Galactosylceramide is a bioactive sphingolipid that inhibits IL-4 production by 53.84% in EL4 T cells when used at a concentration of 10 μM...

A cell-permeable ceramide analog. Induces apoptosis in a variety of cell types. Stimulates ceramide-activated protein phosphatases and activates ceramide-activated protein kinases.C2 ceramide is a...

A useful negative control for C2 Ceramide (Cat. No. 2390-5, 25). Also acts as an autophagy inducer.C2-dihydroceramide is a useful negative control for C2 Ceramide (Cat. No. 2390-5, 25). Also acts as...

5543 | C3aR Antibody DataSheet

Human complement C5a is a 74-amino acid glycopeptide generated during complement activation from the a-chain of complement C5. C5a is a potent chemotactic factor for human peripheral blood...

Mouse complement C5a is a 77-amino acid peptide generated during complement activation from the -chain of complement C5. Mouse C5a shares 60% and 82% amino acid sequence identity to human and rat...

5895 | C5a Antibody DataSheet

Human complement C5a is a 74-amino acid glycopeptide generated during complement activation from the -chain of complement C5. C5a is a potent chemotactic factor for human peripheral blood neutrophils...

Cell-permeable. A reversible, p300/CBP (CREB-binding protein) histone acetyltransferase (HAT) inhibitor (Ki = 400 nM). Specific inhibition to p300 (86%) compared to N-acetyltransferase, PCAF, GCN5,...

C7280948 is an inhibitor of PRMT1 (Protein arginine N-methyltransferase 1) with IC₅₀ value of 12.75 μM. It serves as a useful tool in studying the role of PRMT1 in epigenetics. PMRT1 has been...

C87 is an inhibitor of Tumor Necrosis Factor α (TNFα). It binds to human TNFα with a KD of 110 nM and potently inhibits TNFα-induced cytotoxicity in L929 cells with an IC₅₀ of 8.73 μM. It effectively...

CA 15-3 (Cancer Antigen 15-3) is a breast tumor marker. CA15-3 is a glycoprotein that is secreted by breast cancer cells. While the level of CA15-3 is rarely elevated for patients with early-stage or...

Cancer antigen 19-9 (CA 19-9) is associated with gastrointestinal cancer. An elevated level of CA 19-9 has been reported in various other complications such as colorectal cancer, esophageal cancer,...

Cancer antigen CA 72-4 (CA 72-4) is a biomarker for ovarian cancer. The elevated level of CA 72-4 has been reported in gastrointestinal (GI) cancer patients. Level of Cancer Antigen 72-4 (CA 72-4)...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

CA-074 is an epoxysuccinyl peptide inhibitor of cathepsin B. It selectively inhibits cathepsin B with an IC₅₀ of 2.24 nM over other cysteine proteinases such as cathepsins L and H, and calpains. It...

CA-1001 is a neutral ionophore with high selectivity for Ca²⁺ ions. CA-1001 can be used in microelectrodes for the determination of intracellular Ca2+-activities and of slowly changing Ca²⁺ levels...

Cancer Antigen 125 (CA125) is a surface antigen associated with epithelial ovarian cancer. In serum, CA125 is associated with a high molecular weight glycoprotein. Published studies have indicated...

K7427 | CA19-9 human Elisa Kit DataSheet

Cabazitaxel is a second generation semisynthetic taxane derived from 10-deacetylbaccatin with potent anticancer activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of...

Cabotegravir is a long acting HIV-1 integrase inhibitor that displays activity against a broad range of HIV subtypes.Cabotegravir is a long acting HIV-1 integrase inhibitor that displays activity...

CaCCinh-A01 is a TMEM16 Blocker. It is a non-selective inhibitor of calcium-activated chloride channels (CaCCs) that blocks ATP-stimulated chloride conductance in human salivary gland, intestinal,...

CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC₅₀ of 10 nM. CADD522 treatment results in significant growth inhibition, clonogenic survival, and...

3365R | Cadherin Antibody DataSheet

3365RBP | Cadherin Blocking Peptide DataSheetAntibody Target: Cadherin Accession #: P09803Gene ID: 12550Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

Cyclic ADP-ribose (cADP-ribose) is potent calcium (Ca ²⁺) second messenger. This endogenous metabolite of NAD+ mobilizes the release of stored Ca²⁺ in the endoplasmic reticulum via ryanodine...

A histone-lysine demethylase (HKDM) inhibitor. Inhibits the HDM JMJD2C/KDM4 C and uTX/KDM6A in low µM range.Caffeic acid is a histone-lysine demethylase (HKDM) inhibitor. Inhibits the HDM JMJD2C/KDM4...

E4558 | Caffeine Elisa Kit DataSheet

Caffeine is a popular central nervous system (CNS) stimulant. It is a well-studied substrate of Cytochrome P450 enzymes like CYP1A2. Caffeine is taken up by transporters at the blood brain barrier...

CAL-101 is a cell-permeable inhibitor of the PI3K catalytic subunit p110δ (IC₅₀ = 2.5 nM) that displays 40- to 300-fold selectivity against other PI3K class I enzymes (IC₅₀s = 820, 565, and 89 nM for...

3846BP | Calbindin-28K Blocking Peptide DataSheetAntibody Target: Calbindin-28KAccession #: EDL05596Gene ID: 12307Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

3846 | Calbindin-D-28K Antibody DataSheet

A cell-permeable, non-fluorescent acetoxymethyl ester derivative of Calcein that gets hydrolyzed inside the cell by esterases. The loss of the acetoxymethyl group also enables calcein to readily bind...

3075 | Calcineurin A Antibody DataSheet

3075BP | Calcineurin A Blocking Peptide DataSheetAntibody Target: Calcineurin A Accession #: P16298 Gene ID: 5532Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in...

Calcitonin is a peptide hormone with 32 amino acids and mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is...

An active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). Plays important role in regulating body levels of calcium and phosphorus, and in mineralization of bone. It has...

K409 | Calcium Assay Kit Fluorometric DataSheet

A sterile-filtered solution of Calcium chloride in de-ionized water.Calcium chloride (1 M) sterile solution is a sterile-filtered solution of Calcium chloride in de-ionized water.B1010 | Calcium...

K380 | Calcium Colorimetric Assay Kit DataSheet

E4322 | Calmodulin CALM1 Human Elisa Kit DataSheet

Calmodulin (CaM) is a ubiquitous, calcium-binding protein that can bind to and regulate a multitude of different protein targets, thereby affecting many different cellular functions. CaM mediates...

Calmodulin (CaM) is a ubiquitous, calcium-binding protein that can bind to and regulate a multitude of different protein targets, thereby affecting many different cellular functions. CaM mediates...

Calmodulin is a highly conserved regulatory eukaryotic protein involved in various cellular processes such as glycogen metabolism, cytoskeletal control, neurotransmission, phosphate activity and...

3811 | Calnexin Antibody DataSheet

3811BP | Calnexin Blocking Peptide DataSheetAntibody Target: Calnexin Accession #: P27824Gene ID: 821Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3189 | Calpain 1 Antibody DataSheet

3189BP | Calpain 1I Blocking Peptide DataSheetAntibody Target: Calpain 1 Accession #: P97571Gene ID: 29153Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

K240 | Calpain Activity Fluorometric Assay Kit DataSheet

A cell-permeable inhibitor of calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 0.5 nM). Inhibits neutral cysteine proteases and the proteasome (Ki =...

A cell-permeable inhibitor of calpain 1 (Ki = 120 nM) and calpain 2 (Ki = 230 nM). Also potently inhibits cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM). Shown to induce caspase-dependent...

Z-LLY-FMK is a potent, cell-permeable, and irreversible inhibitor of calpain II. Also acts as an inhibitor of cathepsin L.Z-LLY-FMK is a potent, cell-permeable, and irreversible inhibitor of calpain...

3372 | Calpain-2 Antibody DataSheet

3372BP | Calpain-2 Blocking Peptide DataSheetAntibody Target: Calpain-2 Accession #: NP_001739Gene ID: 824Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

A potent and highly specific cell-permeable protein kinase C (PKC) inhibitor . The inhibition of PKC is light-dependent. Also inhibits PKA, PKG, DAG kinase, phospholipase D1 and D2, myosin light...

3076 | Calreticulin Antibody (Clone S75) DataSheet

3077 | Calreticulin Antibody DataSheet

3077BP | Calreticulin Blocking Peptide DataSheetAntibody Target: Calreticulin Accession #: P27797Gene ID: 811Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the ‘calreticulin/calnexin cycle’ that is responsible...

Calretinin is an intraCellular calcium-binding protein belonging to the troponin C superfamily characterized by a structural motif described as the EF-hand domain. The immunohistochemical detection...

3706 | Calsenilin Antibody DataSheet

3706BP | Calsenilin Blocking Peptide DataSheetAntibody Target: Calsenilin Accession #: Q9Y2W7Gene ID: 30818Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in...

Calyculin A is a very potent inhibitor (Ki = 0.1 nM) with high specificity for the PP-1 and PP-2 classes of protein serine/threonine phosphatase. It is also a potent non-phorbol type tumor promoter...

An inhibitor of NAD-dependent deacetylase activity of human SIRT1 (IC₅₀ = 56 µM) and SIRT2(IC₅₀ = 59 µM). Acts as an antitumor agent. Treatment of BCL6-expressing Burkitt lymphoma cells with Cambinol...

Many of the effects of calcium are mediated via its interaction with calmodulin and the subsequent activation of Ca(2+)/calmodulin-dependent (CaM) kinases. CaM kinases are involved in a wide variety...

Calcium/calmodulin-dependent protein kinase ID (CAMK1D), or a novel Ca2+/calmodulin-dependent kinase I-like kinase (CKLiK), showed kinase activity and that the activity was enhanced by Ca(2+) and...

CLICK-III/CaMKIG is a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK), an isoform of the CaMKI family with an extended C-terminal domain ending with CAAX motif (where...

CAMK4 belongs to the serine/threonine protein kinase family and Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited...

3383 | CaMKII Antibody DataSheet

Camostat mesylate is a synthetic, orally bioavailable is a serine protease inhibitor. Used for the treatment of chronic pancreatitis. It attenuates pancreatic fibrosis via inhibition of monocytes and...

3567 | cAMP Antibody DataSheet

K371 | cAMP Direct Immunoassay Kit Colorimetric DataSheet

Reversibly inhibits nuclear topoisomerase I by binding to and stabilizing the topoisomerase-DNA covalent complex. Inhibits Tat-mediated transcription of HIV-1. Induces apoptosis in Jurkat,...

Canagliflozin is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2), that belongs to a new class of anti-hyperglycaemic agents used in type 2 diabetes mellitus (T2DM).Canagliflozin is...

Cancer Antigen 125 CA-125 human Elisa Kit | K4803

Cancer Antigen 15-3 CA15-3 human Elisa Kit | K4804

A potent small molecule anticancer agent that prevents self-renewal in Cancer Stem Cells (CSCs). Also induces cell death in CSCs and non-stem cancer cells.BBI608 is a potent small molecule anticancer...

Candesartan is an oral angiotensin II receptor blocker (IC50 values are 1.12 and 2.86 nM in bovine adrenal cortex and rabbit aorta, respectively). It is available as a pro-drug, candesartan...

Canertinib is an irreversible tyrosine kinase inhibitor. It not only inhibits tyrosine phosphorylation but also enhances ubiquitinylation and accelerates endocytosis and subsequent intracellular...