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K1416 | Mycoplasma DNA Kit DataSheet

E4664 | Mycoplasma Pneumoniae IgG Elisa Kit DataSheet

E4665 | Mycoplasma Pneumoniae IgM Elisa Kit DataSheet

3244R | MyD88 Antibody DataSheet

3244RBP | MyD88 Blocking Peptide DataSheetAntibody Target: MyD88Accession #: Q6Y1S1Gene ID: 301059Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3831BP | Myeloperoxidase (MPO) Blocking Peptide DataSheetAntibody Target: Myeloperoxidase (MPO) Accession #: EAW94472.1Gene ID: 4353Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50...

A potent, irreversible, and specific inhibitor of the peroxidation activity of myeloperoxidase (MPO; IC₅₀ = 300 nM). Does not affect catalase or glutathione peroxidase activities. Also displays no...

3831 | Myeloperoxidase (MPO) Antibody DataSheet

K744 | Myeloperoxidase MPO Colorimetric Activity Assay Kit DataSheet

K745 | Myeloperoxidase MPO Fluorometric Activity Assay Kit DataSheet

E4579 | Myeloperoxidase MPO Human Elisa Kit DataSheet

K746 | Myeloperoxidase MPO Inhibitor Screening Kit Fluorometric DataSheet

E4580 | Myeloperoxidase MPO Mouse Elisa Kit DataSheet

K747 | Myeloperoxidase MPO Peroxidation Activity Assay Kit DataSheet

E4581 | Myeloperoxidase MPO Rat Elisa Kit DataSheet

Myeloperoxidase (MPO) is a hemeprotein that belongs to the XPO subfamily of the heme peroxidase superfamily.This heme protein catalyzes oxidations by hydrogen peroxide, including MPO- chloride...

MYF-01-37 is a novel covalent inhibitor of TEAD (transcriptional enhanced associate domain) targeting Cys380 when incubated with the TEAD2 protein.MYF-01-37 is a novel covalent inhibitor of TEAD...

MYK-461 is an orally active inhibitor of cardiac myosin ATPase (IC50 = 0.3 µM in purified bovine myosin S1). It displays selectivity for cardiac myosin over skeletal myosin (IC50 = 4.7 µM) and does...

Myoglobin Human Elisa Kit | E4326

E4327 | Myoglobin Mouse Elisa Kit DataSheet

E4328 | Myoglobin Rat Elisa Kit DataSheet

Myoglobin is an oxygen carrier predominantly expressed in skeletal and cardiac muscle cells. The monomeric protein is responsible for the storage and facilitated transport of oxygen from the cell...

Myosin Light Chain is important in the mechanism of contraction in muscle. Once there is an influx of calcium cations (Ca++) into the muscle, either from the sarcoplasmic reticulum or, more...

Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits...

Myostatin, also known as Growth Differentiation Factor-8 (GDF-8), belongs to the TGF- superfamily. Along with other members of the TGF- family, Myostatin plays a crucial role as a regulator for...

A fungal metabolite with potent immunosuppressant activity that is 10-100 fold more compared to Cyclosporin A (Cat. No. 1522). It inhibits serine palmitoyltransferase (Ki = 0.28 nM) blocking the...

N-1-Naphthylphthalamic Acid (NPA) is a polar auxin transport (PAT) inhibitor. It disrupts leaf initiation, KNOX protein regulation, and formation of leaf margins in maize.N-1-Naphthylphthalamic Acid...

N-Acetyl-4-benzoquinone Imine (NAPQI) is a toxic cytochrome P450 3A4 and 2E1 metabolite of Acetaminophen. At therapeutic doses of acetaminophen, NAPQI is inactivated by conjugation with glutathione...

N-Acetyl-L-cysteine is an antioxidant and mucolytic agent. As an antioxidant, NAC scavenges hydrogen peroxide, hydroxyl radical, and hypochlorous acid. Increases cellular pools of free radical...

6781 | N-Cadherin Antibody (Clone # EPR1791-4) DataSheet

N-hydroxysuccinimide is a useful reagent employed to activate a carboxyl group for amide bond formation.N-hydroxysuccinimide is a useful reagent employed to activate a carboxyl group for amide bond...

A non-ionic detergent useful for solubilizing membrane-bound proteins in their native state. Has been shown to increase the resolution of proteins in 2D gels. Due to its high critical micelle...

Oleoyl ethanolamide (OEA) is an analog of the endocannabinoid Anandamide (N-arachidonoylethanolamine; AEA) found in brain tissue. OEA is an endogenous, potent agonist for PPARα, exhibiting an EC₅₀...

N-Oxalylglycine, the amide analog of α-ketoglutarate, is a cell-permeable inhibitor of α-ketoglutarate-dependent enzymes, including JMJD2A, JMJD2C, and JMJD2E (IC₅₀s = 250, 500, and 24 μM,...

N4-Hydroxycytidine is a ribonucleoside analog with broad-spectrum antiviral activity. The prodrug of N4-hydroxycytidine is EIDD-2801. N4-Hydroxycytidine is active against influenza, Ebola, Severe...

6653 | N6-Methyladenosine Antibody DataSheet

N6-Methyladenosine is an adenosine analog that inhibits epinephrine-induced contraction of isolated guinea pig ileum and thoracic aorta. It decreases arterial blood pressure and renal blood flow and...

PMPA is a highly potent and selective inhibitor of NAALADase (N-acetylated-alpha-linked-acidic dipeptidase or glutamate carboxypeptidase II or GCPII) with a Ki value of 275 pM. Displays robust...

NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential...

NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential...

K337 | NAD/NADH Quantitation Colorimetric Kit DataSheet

NADH is a coenzyme that functions as a regenerating electron donor in catabolic processes including glycolysis, beta-oxidation and the citric acid cycle. As a reagent, NADH can be used in enzyme...

NADP⁺ is a coenzyme that is widely distributed in living matter. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).NADP⁺ is a coenzyme...

NADP⁺ is a coenzyme that is widely distributed in living matter. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).NADP, monosodium...

K347 | NADP/NADPH Quantitation Colorimetric Kit DataSheet

NADPH is the reduced form of the coenzyme NADP⁺; used in anabolic reactions such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent.NADPH is the reduced form of the coenzyme...

NAD⁺ is a major electron acceptor molecule in biological oxidations. Acts as a coenzyme for hydride-transfer enzymes and a substrate for NAD(+)-consuming enzymes, which include ADP-ribose...

A broad-spectrum, synthetic serine protease inhibitor and an inhibitor of the classical and alternative ways of complement activation. Displays selectivity for human tryptase when used at relatively...

Naftifine hydrochloride is an allylamine compound that displays antifungal and antimycotic activities. It inhibits fungal squalene epoxidase and prevents ergosterol biosynthesis. Naftifine also shows...

3228 | NAIP Antibody DataSheet

3228BP | NAIP Blocking Peptide DataSheetAntibody Target: NAIP Accession #: Q13075Gene ID: 4671Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate buffered...

Namodenoson (CF-102) is a selective A3 adenosine receptor agonist (Ki = 0.33 nM). Displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectivelyNamodenoson (CF-102) is a selective A3...

K4909 | Nampt Visfatin/PBEF human Intracellular Elisa Kit DataSheet

K4908 | Nampt Visfatin/PBEF mouse/rat Serum Elisa Kit DataSheet

Nampt-IN-1 is a potent and selective NAMPT (Nicotinamide phosphoribosyltransferase) inhibitor. Displays potent anticancer properties. NAMPT is found to be upregulated in various cancer cells and...

Nanaomycin A is a selective DNA methyltransferase 3B (DNMT3B) inhibitor. It induces antiproliferative effects in three different tumor cell lines originating from different tissues. Nanaomycin A...

Nanog is a regulatory protein that is associated with undifferentiated pluripotent cells. The expression of Nanog, which is suppressed in all adult tissues, is restricted to embryonic stem cells and...

Nanog is a regulatory protein that is associated with undifferentiated pluripotent cells. The expression of Nanog, which is suppressed in all adult tissues, is restricted to embryonic stem cells and...

Human Neutrophil activating protein-2 (NAP-2) promotes neutrophil chemotaxis and degranulation. Recombinant human NAP-2 is a 7.6 kDa protein containing 70 amino acid residues.4381 | NAP-2 human...

Naquotinib is a potent, irreversible, third-generation, mutant-selective, epidermal growth factor receptor (EGFR) inhibitor that displays antineoplastic activity. Naquotinib preferentially inhibits...

Narasin is an ionophore antibiotic which is a derivative of salinomycin. It modifies the permeability of cellular membranes to cationic metal species. It inhibits NF-κB signaling via inhibition of...

The major flavanone found in grapefruit. Acts as an antioxidant, free radical scavenger and carbohydrate metabolism promoter. Shows cytotoxicity in various human cell lines and promotes apoptosis in...

Natamycin is a naturally-occurring macrolide polyene antibiotic that acts as an antifungal agent. Natamycin blocks fungal growth by binding specifically to ergosterol with an apparent affinity of...

Nateglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues,...

Prostate specific antigen (PSA) is a kallikrein, a subgroup of serine proteases with diverse physiological functions. PSA is synthesized in the epithelial cells of the grostate gland, and is present...

3838 | NATL/LAB Antibody DataSheet

Nazartinib is a potent, irreversible, third-generation, mutant-selective epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity. It covalently binds to and inhibits...

NBQX is a potent, selective and competitive AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor antagonist. It targets both AMPA- and kainate-sensitive glutamate receptors (IC₅₀ = 0...

NCB-0846 is a potent small-molecule TNIK (Traf2 and Nck-interacting protein kinase) inhibitor, having anti-Wnt activity and suppressing Wnt-driven intestinal tumorigenesis. Also inhibits FLT3, JAK3,...

NCC007 is an inhibitor of casein kinase I (CKI) and a modulator of circadian rhythm. It inhibits CKIα and CKIδ with an IC₅₀ of 1.8 and 3.6 μM. It shows stronger period effects (0.32 μM for 5 h period...

A1160 | NCF1 Antibody DataSheet

NCGC00244536 is a potent KDM4A inhibitor (IC₅₀ = 10 nM). NCGC00244536 displays high selectivity for the fast-growing AR-negative PC3 cells (IC₅₀ = 40 nM) and over 100-fold selectivity against the...

NCH-51 (PTACH) is a cell-permeable prodrug that is intracellularly converted to a potent HDAC inhibitor (IC₅₀ of 48 nM). PTACH is predicted to exhibit a similar HDAC binding mode as that of SAHA,...

3693 | NCS-1 Antibody DataSheet

3693BP | NCS-1 Blocking Peptide DataSheetAntibody Target: NCS-1 Accession #: AAP97256Gene ID: 23413Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

ND-630 is potent, and reversible acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC₅₀ values of 2.1 and 6.1 nM, respectively. When administered chronically to Zucker...

NDGA is a a phenolic compound isolated from the creosote bush Larrea divaricatta that has anti-cancer activities both in vitro and in vivo. NDGA acts as a non-selective lipoxygenase (LO) inhibitor...

3526BP | NDRG1 Blocking Peptide DataSheetAntibody Target: NDRG1 Accession #: Q92597Gene ID: 10397Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

A non-detergent sulfobetaine (NDSB) that prevents protein aggregation and facilitates the renaturation of chemically and thermally denatured proteins. The non-detergent sulfobetaine is zwitterionic,...

A non-detergent sulfobetaine (NDSB) that prevents protein aggregation and facilitates the renaturation of chemically and thermally denatured proteins. The non-detergent sulfobetaine is zwitterionic,...

A non-detergent sulfobetaine (NDSB) that prevents protein aggregation and facilitates the renaturation of chemically and thermally denatured proteins. The non-detergent sulfobetaine is zwitterionic,...

A non-detergent sulfobetaine (NDSB) that prevents protein aggregation and facilitates the renaturation of chemically and thermally denatured proteins. The non-detergent sulfobetaine is zwitterionic,...

A non-detergent sulfobetaine (NDSB) that prevents protein aggregation and facilitates the renaturation of chemically and thermally denatured proteins. The non-detergent sulfobetaine is zwitterionic,...

NE-100 is a potent antagonist of sigma-1 (σ1) receptor. It inhibits binding of (+)-pentazocine binding to sigma-1 binding sites with an IC₅₀ value of 1.54 nM. NE-100 attenuates phencyclidin induced...

A potent necroptosis inhibitor. Displays higher activity in inhibiting necroptosis in Jurkat cells than Nec-1 (Cat. No. 1864) (EC₅₀ = 210 nM versus EC₅₀ = 490 nM), as well as showing no nonspecific...

NECA is a high affinity adenosine receptor agonist (Ki values are 6.2, 14, and 20 nM for human A3, A1 and A2A receptors respectively; EC₅₀ = 2.4 μM for human A2B). NECA is also reported to act as a...

A cell-permeable necrosis inhibitor that displays antioxidant property. It localizes mostly in the mitochondria. Selectively blocks oxidative stress-induced necrotic cell death (0.1 µM NecroX-2...

A cell-permeable necrosis inhibitor that displays antioxidant property. It localizes mostly in the mitochondria. Selectively blocks oxidative stress-induced necrotic cell death (0.1 µM NecroX-5...

Inhibits necroptosis, a non-apoptotic cell death pathway. Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. Inhibits RIP1 kinase, the key upstream kinase involved in...

Inhibits non-apoptotic cell death pathway by inhibition of the death domain receptor-associated adaptor kinase RIP1. Three distinct mechanisms appear to be involved in necroptosis, the alternative...

A necroptosis inhibitor. The biological activity of necrostatin-7 (Nec-7) is different from that of necrostatin-1 to -5 as Nec-7 does not inhibit RIP1 kinase. Nec-7 may target an additional...

Necrosulfonamide is a potent necroptosis inhibitor. It blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during...

3821 | Nectin-3/CD113 Antibody DataSheet

3821BP | Nectin-3/CD113 Blocking Peptide DataSheetAntibody Target: Nectin-3/CD113 Accession #: Q9NQS3Gene ID: 25945Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml)...

Nedaplatin is an analog of platinum-based anti-cancer drugs such as carboplatin and cisplatin. It has cytotoxic activity in human ovarian tumors. The administration of either nedaplatin or cisplatin...

Prepared by the C-terminal derivatisation of NEDD8 with 7-amino-4-methylcoumarin. NEDD8-AMC acts as a useful and sensitive fluorogenic substrate for deNEDDylating enzymes, including NEDP1 and UCH-L3...

Nelfinavir is an orally bioavailable inhibitor of the HIV-1 protease (Ki =2 nM) that is used in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection. In vivo,...

Nek 2 is closely related in its catalytic domain to the serine/threonine protein kinase NIMA of Aspergillus nidulans that is required for entry into mitosis and may function in parallel to the...

Nek2/Hec1 inhibitor targets the Hec1/Nek2 pathway and causes chromosome mis-alignment as well as cell death. The IC₅₀ for cytotoxicity in MDA-MB231, MDA-MB468, HeLa and K562 cell lines is 1.1 μM, 3.4...

Nek6 is a serine/threonine kinase that is a member of the Nek family of protein kinases that share an amino-terminal catalytic domain related to NIMA (never in mitosis, gene A) family (1). Nek6 is a...