3-Bromo-7-nitroindazole | 2361

A more potent inhibitor of nNOS than 7-nitroindazole (Cat. No. 2360) in vitro, but unlike 7-nitroindazole, it is also potent against iNOS. The IC₅₀ values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.17, 0.86, and 0.29 µM, respectively.

3-Bromo-7-nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole (Cat. No. 2360) in vitro, but unlike 7-nitroindazole, it is also potent against iNOS.

2361 | 3-Bromo-7-nitroindazole DataSheet

Alternate Name/Synonyms: 3-​bromo-​7-​nitro-​1H-​indazole

Appearance: Light brown solid

Formulation: N/A

CAS Number: 74209-34-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₇H₄BrN₃O₂

Molecular Weight: 242.03

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO (~ 25 mg/ml) or EtOH (~12 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A potent nitric oxide synthase (NOS) inhibitor

MDL Number: MFCD00159910

PubChem CID: 1649

SMILES: C1=CC2=C(NN=C2C(=C1)[N+](=O)[O-])Br

InChi: InChI=1S/C7H4BrN3O2/c8-7-4-2-1-3-5(11(12)13)6(4)9-10-7/h1-3H,(H,9,10)

InChi Key: NFSTZPMYAZRZPC-UHFFFAOYSA-N