7-Nitroindazole | 2360

A non-selective, reversible and competitive inhibitor of NOS isoforms in vitro. The IC₅₀ values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.71, 0.78, and 5.8 µM, respectively. However, it shows good anti-nociceptive effects in vivo without affecting blood pressure via inhibition of eNOS.

7-Nitroindazole is a non-selective, reversible and competitive inhibitor of NOS isoforms in vitro. The IC₅₀ values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.71, 0.78, and 5.8 µM, respectively.

2360 | 7-Nitroindazole DataSheet

Alternate Name/Synonyms: 7-​nitro-​1H-​indazole; 7-NI

Appearance: Brown solid

Formulation: N/A

CAS Number: 2942-42-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₇H₅N₃O₂

Molecular Weight: 163.13

Cell-Permeable?: Yes

Purity: ≥97% by GC

Solubilities: DMSO (~ 15 mg/ml) or EtOH (~4 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A non-selective, reversible and competitive inhibitor of NOS isoforms in vitro.

MDL Number: MFCD00022789

PubChem CID: 1893

SMILES: C1=CC2=C(C(=C1)[N+](=O)[O-])NN=C2

InChi: InChI=1S/C7H5N3O2/c11-10(12)6-3-1-2-5-4-8-9-7(5)6/h1-4H,(H,8,9)

InChi Key: PQCAUHUKTBHUSA-UHFFFAOYSA-N