3-Deazaadenosine | 2771

3-Deazaadenosine (3-DZA) is an inhibitor of SAH (S-adenosylhomocysteine) hydrolase (Ki = 3.9 μM). It has anti-inflammatory properties, inhibiting leukocyte adhesion and chemotaxis, lymphocyte-mediated cytolysis, phagocytosis, degranulation, and NF-κB signaling. 3-DZA also has anti-viral and anti-bacterial activities.

3-Deazaadenosine (3-DZA) is an inhibitor of SAH (S-adenosylhomocysteine) hydrolase (Ki = 3.9 μM). It has anti-inflammatory properties, inhibiting leukocyte adhesion and chemotaxis, lymphocyte-mediated cytolysis, phagocytosis, degranulation, and NF-κB signaling. 3-DZA also has anti-viral and anti-bacterial activities.

2771 | 3-Deazaadenosine DataSheet

Alternate Name/Synonyms: 1-​β-​D-​ribofuranosyl-​1H-​Imidazo[4,​5-​c]pyridin-​4-​amine; 3-DZA; deaza-Ado; c3Ado

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 6736-58-9

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₁H₁₄N₄O₄

Molecular Weight: 266.25

Cell-Permeable?: Y

Purity: ≥98%

Solubilities: H₂O (~10 mg/ml)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A SAH hydrolase inhibitor

MDL Number: MFCD00153951

PubChem CID: 23190

SMILES: C1=CN=C(C2=C1N(C=N2)C3C(C(C(O3)CO)O)O)N

InChi: InChI=1S/C11H14N4O4/c12-10-7-5(1-2-13-10)15(4-14-7)11-9(18)8(17)6(3-16)19-11/h1-2,4,6,8-9,11,16-18H,3H2,(H2,12,13)/t6-,8-,9-,11-/m1/s1

InChi Key: DBZQFUNLCALWDY-PNHWDRBUSA-N