3-Methyladenine | 2249

Commonly used as a specific inhibitor of autophagic sequestration. 3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K).

3-Methyladenine is a specific inhibitor of autophagic sequestration. 3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K).

2249 | 3-Methyladenine DataSheet

Alternate Name/Synonyms: 3-Methyl-3H-purin-6-amine; 3-MA; NSC 66389

Appearance: White solid

Formulation: N/A

CAS Number: 5142-23-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₆H₇N₅

Molecular Weight: 149.15

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO (50 mM)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A specific autophagy inhibitor

MDL Number: MFCD00010531

PubChem CID: 1673

SMILES: CN1C=NC(=C2C1=NC=N2)N

InChi: InChI=1S/C6H7N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h2-3H,7H2,1H3

InChi Key: FSASIHFSFGAIJM-UHFFFAOYSA-N