3-Nitropropionic acid | 2093

A plant and fungal toxin, 3-nitropropionic acid acts as an irreversible inactivator of succinate dehydrogenase. Selectively inhibits succinic dehydrogenase complex (Complex II) in the mitochondrial electron transport chain. Also shown to cause brain lesions similar to those of Huntington′s disease.

3-Nitropropionic acid is a plant and fungal toxin, 3-nitropropionic acid acts as an irreversible inactivator of succinate dehydrogenase. Selectively inhibits succinic dehydrogenase complex (Complex II) in the mitochondrial electron transport chain. Also shown to cause brain lesions similar to those of Huntington′s disease.

2093 | 3-Nitropropionic acid DataSheet

Alternate Name/Synonyms: 3-NP

Appearance: Colorless to slight yellow solid

Formulation: N/A

CAS Number: 504-88-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₃H₅NO₄

Molecular Weight: 119.08

Cell-Permeable?: No

Purity: ≥97% by titration

Solubilities: Ethanol (~100 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An irreversible inactivator of succinate dehydrogenase.

MDL Number: MFCD00007406

PubChem CID: 1678

SMILES: C(C[N+](=O)[O-])C(=O)O

InChi: InChI=1S/C3H5NO4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)

InChi Key: WBLZUCOIBUDNBV-UHFFFAOYSA-N