3PO | B2018

3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO reduces glycolytic flux and suppresses glucose uptake. 3PO may be a useful agent in combination with other drugs that inhibit cancer cell proliferation.

3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO reduces glycolytic flux and suppresses glucose uptake. 3PO may be a useful agent in combination with other drugs that inhibit cancer cell proliferation.

B2018 | 3PO DataSheet

Alternate Name/Synonyms: 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one

Appearance: Yellow solid

Formulation: N/A

CAS Number: 13309-08-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₃H₁₀N₂O

Molecular Weight: 210.24

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO (>20 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor

MDL Number: N/A

PubChem CID: 5720233

SMILES: C1=CC(=CN=C1)C=CC(=O)C2=CC=NC=C2

InChi: InChI=1S/C13H10N2O/c16-13(12-5-8-14-9-6-12)4-3-11-2-1-7-15-10-11/h1-10H/b4-3+

InChi Key: UOWGYMNWMDNSTL-ONEGZZNKSA-N