4-1BBL, human recombinant | 4369

Human 4-1BB Ligand (4-1BBL) is a member of the emerging family of Ligands with structural homology to tumor necrosis factor. Recombinant human 4-1BBL is a 19.5 kDa protein containing 185 amino acid residues, comprising the TNF-like extra-Cellular domain of 4-1BBL.

4369 | 4-1BBL human recombinant DataSheet

Biomolecule/Target: 4-1BBL

Synonyms: TNFSF9, CD137L

Alternates names: TNFSF9, CD137L

Taglines: A transmembrane cytokine

NCBI Gene ID #: 3952

NCBI Gene Symbol: LEP

Gene Source: Human

Accession #: P41159

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g

Activity (Specifications/test method): N/A

Biological activity: ’s human Leptin has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 mg Leptin/gm of body weight for 7 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed to saline-treated controls.

Results: 10 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 16.0 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized from 5 mM Tris, pH 8.0 + 75 mM NaCl.

Reconstitution Instructions: Add 15 mM sterile HCl (0.5 ml/1 mg vial or 5 ml/10 mg vial) to the vial. After the protein is completely dissolved, add 7.5 mM sterile NaOH (0.3 ml/1 mg vial or 3 ml/10 mg vial) to bring the pH to approximately 5.2.

Amino acid sequence: N/A