4-1BBR, human recombinant | 4370

Human 4-1BB Receptor (4-1BBR) is an inhibitor of 4-1BBL and can block 4-1BBL bioactivity. Recombinant human 4-1BBR is a 17.8 kDa protein containing 167 amino acid residues of extraCellular domain of 4-1BBR without signal peptide (Gene accession # NP_001552).

4370 | 4-1BB Receptor human recombinant DataSheet

Biomolecule/Target: 4-1BB Receptor

Synonyms: TNFRSF9, CD137 antigen, T-cell antigen ILA

Alternates names: TNFRSF9, CD137 antigen, T-cell antigen ILA

Taglines: A transmembrane cytokine receptor

NCBI Gene ID #: 3604

NCBI Gene Symbol: TNR9

Gene Source: Human

Accession #: Q07011

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: 98%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g

Activity (Specifications/test method): N/A

Biological activity: Determined by its inhibitory effect of the 4-1BBL mediated stimulation of IL-8 production by human PBMC. About 90% of inhibition was seen using a concentration of 1 µg for both 4-1BBL and 4-1BBR.

Results: 1 µg

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 17.8 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized with no additives

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A