4SC-202 | B1230

4SC-202 is an orally available potent HDAC inhibitor (HDACi) specific for class I HDAC isoenzymes with IC50s of 1.2/1.12/0.57 µM for HDAC1/2/3; displays high selectivity over ClassIIa/IIb/III HDACs. Displays antineoplastic activity.

4SC-202 is an orally available potent HDAC inhibitor (HDACi) specific for class I HDAC isoenzymes with IC50s of 1.2/1.12/0.57 µM for HDAC1/2/3; displays high selectivity over ClassIIa/IIb/III HDACs. Displays antineoplastic activity.

B1230 | 4SC-202 DataSheet

Alternate Name/Synonyms: E)-N-(2-aminophenyl)-3-(1-((4-(1-methyl-1H-pyrazol-4-yl)phenyl)sulfonyl)-1H-pyrrol-3-yl)acrylamide tosylic acid

Appearance: Yellow Solid

Formulation: N/A

CAS Number: 1186222-89-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: Yes

Molecular Formula: C₃₀H₂₉N₅O₆S₂

Molecular Weight: 619.71

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO(> 50 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: SC-202 is an orally bioavailable HDAC inhibitor

MDL Number: N/A

PubChem CID: 44217246

SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.CN1C=C(C=N1)C2=CC=C(C=C2)S(=O)(=O)N3C=CC(=C3)C=CC(=O)NC4=CC=CC=C4N

InChi: InChI=1S/C23H21N5O3S.C7H8O3S/c1-27-16-19(14-25-27)18-7-9-20(10-8-18)32(30,31)28-13-12-17(15-28)6-11-23(29)26-22-5-3-2-4-21(22)24;1-6-2-4-7(5-3-6)11(8,9)10/h2-16H,24H2,1H3,(H,26,29);2-5H,1H3,(H,8,9,10)/b11-6+;

InChi Key: IAVXAZDVNICKFJ-ICSBZGNSSA-N