5-Fluoroorotic acid monohydrate (5-FOA) | 2796

5-Fluoroorotic Acid (5-FOA) is used in yeast molecular genetics to detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) decarboxylase. 5-FOA is toxic to yeast cells that can synthesize the enzyme orotidine-5’-phosphate decarboxylase and are therefore unable to grow in 5-FOA-containing media.

5-Fluoroorotic Acid (5-FOA) is used in yeast molecular genetics to detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) decarboxylase. 5-FOA is toxic to yeast cells that can synthesize the enzyme orotidine-5’-phosphate decarboxylase and are therefore unable to grow in 5-FOA-containing media.

2796 | 5-Fluoroorotic acid monohydrate (5-FOA) DataSheet

Alternate Name/Synonyms: 2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid; 5-Fluorouracil-4-carboxylic acid; 5-Fluorouracil-4-carboxylic acid hydrate

Appearance: Off-white to yellow solid

Formulation: N/A

CAS Number: 207291-81-4, 220141-70-8

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₅H₃FN₂O₄.H₂O

Molecular Weight: 192.1

Cell-Permeable?: No

Purity: ≥97% by titration

Solubilities: DMSO (>100 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A Yeast genetic counter-selection agent

MDL Number: MFCD00150658

PubChem CID: 16212749

SMILES: C1(=C(NC(=O)NC1=O)C(=O)O)F.O

InChi: InChI=1S/C5H3FN2O4.H2O/c6-1-2(4(10)11)7-5(12)8-3(1)9;/h(H,10,11)(H2,7,8,9,12);1H2

InChi Key: LODRRYMGPWQCTR-UHFFFAOYSA-N