5-Fluorouracil | B1519

5-Fluorouracil (5-FU) is an anticancer agent that gets metabolized to form fluorodeoxyuridine monophosphate (FdUMP), fluorodeoxyuridine triphosphate (FdUTP) and fluorouridine (FUTP). FdUMP inhibits thymidylate synthase, causing a reduction in dTMP synthesis. FUTP and FdUTP are misincorporated into RNA and DNA respectively.

5-Fluorouracil (5-FU) is an anticancer agent that gets metabolized to form fluorodeoxyuridine monophosphate (FdUMP), fluorodeoxyuridine triphosphate (FdUTP) and fluorouridine (FUTP). FdUMP inhibits thymidylate synthase, causing a reduction in dTMP synthesis. FUTP and FdUTP are misincorporated into RNA and DNA respectively.

B1519 | 5-Fluorouracil DataSheet

Alternate Name/Synonyms: 5-Fluoro-2,4-(1H,3H)-pyrimidinedione; 5-FU

Appearance: White solid

Formulation: N/A

CAS Number: 51-21-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₄H₃FN₂O₂

Molecular Weight: 130.08

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An anticancer agent

MDL Number: MFCD00006018

PubChem CID: 3385

SMILES: C1=C(C(=O)NC(=O)N1)F

InChi: InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)

InChi Key: GHASVSINZRGABV-UHFFFAOYSA-N