5-Fluorouridine | B3149

5-Fluorouridine is a ribonucleotide metabolite of 5-Fluorouracil. It is cytotoxic and inhibits rRNA synthesis in human colon carcinoma cells. It exhibits cytotoxic effect on lymphoma cells with an IC₅₀ of 2 nM.

5-Fluorouridine is a ribonucleotide metabolite of 5-Fluorouracil. It is cytotoxic and inhibits rRNA synthesis in human colon carcinoma cells. It exhibits cytotoxic effect on lymphoma cells with an IC₅₀ of 2 nM.

B3149 | 5-Fluorouridine DataSheet

Alternate Name/Synonyms: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione; 5-Fur; 1-(b-D-Ribofuranosyl)-5-fluorouracil; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; Furd

Appearance: White to off-white powder

Formulation:

CAS Number: 316-46-1

Structure Available?: TRUE

Peptide sequence:

Salt Form: FALSE

Molecular Formula: C₉H₁₁FN₂O₆

Molecular Weight: 262.19

Cell-Permeable?: TRUE

Purity: ≥ 98%

Solubilities: ~50 mg/ml in water

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A ribonucleotide metabolite of 5-Fluorouracil with anticancer activity

MDL Number: MFCD00036832

PubChem CID: 9427

SMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)F

InChi: InChI=1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1

InChi Key: FHIDNBAQOFJWCA-UAKXSSHOSA-N