5-Lipoxygenase, Active, Human Recombinant | P1373

Lipoxygenases are non-heme iron-containing dioxygenases. These enzymes convert unsaturated fatty acids to epoxides, such as leukotrienes from arachidonic acid. They play an important role in cell proliferation, differentiation and inflammation; and have been implicated in inflammation and hyper proliferation mediated diseases like asthma, rheumatoid arthritis and cancer.

P1373 | 5-Lipoxygenase Active Human Recombinant DataSheet

Biomolecule/Target: 5-Lipoxygenase

Synonyms: ALOX5, 5-LOX, Arachidonate 5-lipoxygenase

Alternates names: ALOX5, 5-LOX, Arachidonate 5-lipoxygenase

Taglines: Non-heme iron-containing dioxygenases

NCBI Gene ID #: 240

NCBI Gene Symbol: ALOX5

Gene Source: Human

Accession #: P09917

Recombinant: TRUE

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): 300 µU/mg. The enzyme’s activity was assayed using ’s Lipoxygenase Activity Assay Kit (Catalog Number: K978).

Biological activity: N/A

Results: 300 µU/mg

Binding Capacity: N/A

Unit Definition: One unit is the amount of enzyme that will hydrolyze 1.0 µmole of arachidonic acid at pH 7.4 and 25 C.

Molecular Weight: 68.3 kDa (1-579 aa + N-terminal His Tag)

Concentration: N/A

Appearance: Liquid

Physical form description: Liquid

Reconstitution Instructions: N/A

Amino acid sequence: 1-579 aa