5-LO Inhibitor, CDC | B3341

5-LO Inhibitor, CDC | B3341

Description: CDC is a potent and direct inhibitor of 5-LO (5-lipoxygenase). CDC reduces 5-LO activity in cell-free assays (purified human recombinant enzyme or leukocyte homogenates), with IC50 values in the low nanomolar range (9–25 nM) and a selectivity index of approximately 35 and 15 over p12-LO and 15-LO1, respectively.

Alternate Name/Synonyms: CDC Cinnamyl-3,4-dihydroxy-α-cyanocinnamate

Appearance: Light yellow to yellow powder

Formulation:

CAS Number: 132465-11-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₁₅NO₄

Molecular Weight: 321.33

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: >5 mg/ml Ethanol >5 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of >Tag Line: A potent 5-LO (5-Lipoxygenase) inhibitor

MDL Number: MFCD00210839

PubChem CID: 14840979

PubChem CID Link: https://pubchem.ncbi.nlm.nih.gov/compound/14840979

SMILES: C1=CC=C(C=C1)C=CCOC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N

InChi: InChI=1S/C19H15NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-9,11-12,21-22H,10H2/b7-4+,16-11+

InChi Key: XGHYFEJMJXGPGN-UYHGDYIZSA-N

Category: Biochemicals