680C91 | 2292

Cell-permeable. A potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO, Ki = 51 nM.) Tryptophan is metabolized to the endogenous AHR ligand by TDO which may be inhibited by 680C91. Active in vivo.

680C91 is a potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO, Ki = 51 nM. Tryptophan is metabolized to the endogenous AHR ligand by TDO which may be inhibited by 680C91. Active in vivo.

2292 | 680C91 DataSheet

Alternate Name/Synonyms: 6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-1H-indole

Appearance: Light brown solid

Formulation: N/A

CAS Number: 163239-22-3

Structure Available?: Yes

Peptide sequence: No

Salt Form: No

Molecular Formula: C₁₅H₁₁FN₂

Molecular Weight: 238.26

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~25 mg/ml) or EtOH (~10 mg/ml)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A potent and selective tryptophan 2,3-dioxygenase (TDO) inhibitor

MDL Number: MFCD20926361

PubChem CID: 10014426

SMILES: C1=CC(=CN=C1)C=CC2=CNC3=C2C=CC(=C3)F

InChi: InChI=1S/C15H11FN2/c16-13-5-6-14-12(10-18-15(14)8-13)4-3-11-2-1-7-17-9-11/h1-10,18H/b4-3+

InChi Key: YBSDQTBCNYWBMX-ONEGZZNKSA-N