7,3',4'-Trihydroxyisoflavone | 1886

An ATP-competitive inhibitor of Cot and MKK4 that subsequently suppresses UVB-induced COX-2 expression in JB6 P+ mouse epidermal cells.

7,3',4'-Trihydroxyisoflavonem is an ATP-competitive inhibitor of Cot and MKK4 that subsequently suppresses UVB-induced COX-2 expression in JB6 P+ mouse epidermal cells.

1886 | 7,3',4'-Trihydroxyisoflavone DataSheet

Alternate Name/Synonyms: 3-(3,4-Dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one; 3’-Hydroxydiadzein; THIF; 7,3’,4’-THIF

Appearance: Off-white solid

Formulation: N/A

CAS Number: 485-63-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₀O₅

Molecular Weight: 270.24

Cell-Permeable?: No

Purity: ≥98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An ATP-competitive inhibitor of Cot and MKK5

MDL Number: MFCD00143002

PubChem CID: 5284648

SMILES: C1=CC(=C(C=C1C2=COC3=C(C2=O)C=CC(=C3)O)O)O

InChi: InChI=1S/C15H10O5/c16-9-2-3-10-14(6-9)20-7-11(15(10)19)8-1-4-12(17)13 (18)5-8/h1-7,16-18H

InChi Key: DDKGKOOLFLYZDL-UHFFFAOYSA-N