7BIO | 9690

7BIO is a caspase- independent nonapoptotic cell death inducer. Also acts as an ATP-competitive FLT3 inhibitor and DYRK1A and DYRK 2 (Dual-specificity tyrosine phosphorylation-regulated kinase) inhibitor. In addition, 7BIO is a necrosis inducer and inflammasome activator. Also a potent inhibitor of Aurora kinase B and C.

7BIO is a caspase- independent nonapoptotic cell death inducer. Also acts as an ATP-competitive FLT3 inhibitor and DYRK1A and DYRK 2 (Dual-specificity tyrosine phosphorylation-regulated kinase) inhibitor. In addition, 7BIO is a necrosis inducer and inflammasome activator. Also a potent inhibitor of Aurora kinase B and C.

9690 | 7BIO DataSheet

Alternate Name/Synonyms: 7-Bromoindirubin-3'-oxime

Appearance: Dark red solid

Formulation: N/A

CAS Number: 916440-85-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₀BrN₃O₂

Molecular Weight: 356.2

Cell-Permeable?: Yes

Purity: ≥98% by NMR

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A caspase- independent nonapoptotic cell death inducer and an inflammasome activator

MDL Number: N/A

PubChem CID: 11846148

SMILES: C1=CC=C2C(=C1)C(=C(N2)C3=C4C=CC=C(C4=NC3=O)Br)NO

InChi: InChI=1S/C16H10BrN3O2/c17-10-6-3-5-9-12(16(21)19-13(9)10)15-14(20-22)8-4-1-2-7-11(8)18-15/h1-7,18,20,22H

InChi Key: MGVCNALPOHOEQM-UHFFFAOYSA-N