8-Azaadenosine | B2572

8-Azaadenosine is an ADAR1 (adenosine deaminases acting on double-stranded RNA) inhibitor. Reduces A-to-I editing activity in a leukemia cell line, restores let-7 and inhibits leukemia stem cells self-renewal in vitro. Acts as an inhibitor of ovarian cancer stem like cells (CSCs).

8-Azaadenosine is an ADAR1 (adenosine deaminases acting on double-stranded RNA) inhibitor. Reduces A-to-I editing activity in a leukemia cell line, restores let-7 and inhibits leukemia stem cells self-renewal in vitro. Acts as an inhibitor of ovarian cancer stem like cells (CSCs).

B2572 | 8-Azaadenosine DataSheet

Alternate Name/Synonyms: 8-AzaAdo, NSC72961, 3-β-D-Ribofuranosyl-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine

Appearance: White solid

Formulation:

CAS Number: 10299-44-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₉H₁₂N₆O₄

Molecular Weight: 268.23

Cell-Permeable?: True

Purity: ≥97% by HPLC

Solubilities: >25 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An ADAR1 inhibitor

MDL Number:

PubChem CID: 96410

SMILES: C1=NC(=C2C(=N1)N(N=N2)C3C(C(C(O3)CO)O)O)N

InChi: InChI=1S/C9H12N6O4/c10-7-4-8(12-2-11-7)15(14-13-4)9-6(18)5(17)3(1-16)19-9/h2-3,5-6,9,16-18H,1H2,(H2,10,11,12)/t3-,5-,6-,9-/m1/s1

InChi Key: OAUKGFJQZRGECT-UUOKFMHZSA-N