8-Hydroxy-2'-deoxyguanosine | 2177

8-Hydroxy-2-deoxyguanosine is produced by oxidative damage of DNA by reactive oxygen and nitrogen species, including hydroxyl radical and peroxynitrite. It serves as a critical biomarker of oxidative stress and carcinogenesis.

8-Hydroxy-2-deoxyguanosine is produced by oxidative damage of DNA by reactive oxygen and nitrogen species. It serves as a critical biomarker of oxidative stress and carcinogenesis.

2177 | 8-Hydroxy-2'-deoxyguanosine DataSheet

Alternate Name/Synonyms: 8-Oxo-dG; 8-Oxo-7,8-dihydrodeoxyguanosine; 8-Hydroxydeoxyguanosine; 7,8-Dihydro-8-oxo-2’-deoxyguanosine; sine; 8-OH-dG

Appearance: White to Off-white Solid

Formulation: N/A

CAS Number: 88847-89-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₀H₁₃N₅O₅

Molecular Weight: 283.24

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 12 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A critical biomarker of oxidative stress and carcinogenesis

MDL Number: MFCD00210311

PubChem CID: 73318

SMILES: C1C(C(OC1N2C3=C(C(=O)N=C(N3)N)NC2=O)CO)O

InChi: InChI=1S/C10H13N5O5/c11-9-13-7-6(8(18)14-9)12-10(19)15(7)5-1-3(17)4(2-16)20-5/h3-5,16-17H,1-2H2,(H,12,19)(H3,11,13,14,18)/t3-,4+,5+/m0/s1

InChi Key: HCAJQHYUCKICQH-VPENINKCSA-N