8-Hydroxyguanosine | DNA/RNA oxidative damage (clone 15A3) | AS10 708-100

8-Hydroxyguanosine | DNA/RNA oxidative damage (clone 15A3) | AS10 708-100 | Gentaur UK, US & Europe Distribution

Immunogen: 8-hydroxy-guanosine-BSA and - casein conjugates

Host: Mouse

Conjugation: N/A

Clonality: Monoclonal

Isotype: IgG2A

Purity: Total IgG fraction. Protein G purified.

Format: Liquid

Tested Application: ELISA (ELISA), Immunoaffinity chromatography (IAP), Immunohistochemistry on frozen tissue and paraffin-embedded (IHC-Fr-P)

Related Products: AS10 708-25 | Anti- hydroxy guanosine monoclonal antibodies, 25 µgSecondary antibodies

Recommended Dilutions: The optimal working dilution should be determined by the investigator

Molecular weight: N/A

Confirmed Reactivity: Recognizes markers of oxidative damage to DNA (8-hydroxy-2'-deoxyguanosine, 8-hydroxyguanine and 8-hydroxyguanosine)

Predicted Reactivity: N/A

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: Protocol for immunostaining using this antibody can be found here.

Background: Oxidative derivate of guanosine is called 8-Hydroxyguanosine (8OHdG) and is used as a popular biomarker of oxidative stress.

Reconstitution: N/A

Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Oxidative stress

Research Area: Proteomics