Description
A-1155463 is a highly potent and selective BCL-XL inhibitor. A-1155463 is more potent against BCL-XL-dependent cell lines relative to WEHI-539 (Cat. No. B1819), while possessing none of its inherent pharmaceutical liabilities.
A-1155463 is a highly potent and selective BCL-XL inhibitor. A-1155463 is more potent against BCL-XL-dependent cell lines relative to WEHI-539 (Cat. No. B1819), while possessing none of its inherent pharmaceutical liabilities.
Alternate Name/Synonyms: 2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(3-(4-(3-(dimethylamino)prop-1-yn-1-yl)-2-fluorophenoxy)propyl)thiazole-4-carboxylic acid
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1235034-55-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₃₅H₃₂FN₅O₄S₂
Molecular Weight: 669.79
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A highly potent and selective BCL-XL inhibitor.
MDL Number: N/A
PubChem CID: 59447577
SMILES: CN(C)CC#CC1=CC(=C(C=C1)OCCCC2=C(N=C(S2)N3CCC4=CC=CC(=C4C3)C(=O)NC5=NC6=CC=CC=C6S5)C(=O)O)F
InChi: InChI=1S/C35H32FN5O4S2/c1-40(2)17-6-8-22-14-15-28(26(36)20-22)45-19-7-13-30-31(33(43)44)38-35(47-30)41-18-16-23-9-5-10-24(25(23)21-41)32(42)39-34-37-27-11-3-4-12-29(27)46-34/h3-5,9-12,14-15,20H,7,13,16-19,21H2,1-2H3,(H,43,44)(H,37,39,42)
InChi Key: SOYCFODXNRVBTI-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |