A-1331852 | B1948

A-1331852 is a potent anti-apoptotic Bcl-xL protein inhibitor and apoptosis-inducing agent useful in the treatment of cancer, immune and autoimmune diseases.

A-1331852 is a potent anti-apoptotic Bcl-xL protein inhibitor and apoptosis-inducing agent useful in the treatment of cancer, immune and autoimmune diseases.

B1948 | A-1331852 DataSheet

Alternate Name/Synonyms: 3-(1-(adamantan-1-ylmethyl)-5-methyl-1H-pyrazol-4-yl)-6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl) picolinic acid

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1430844-80-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₈H₃₈N₆O₃S

Molecular Weight: 658.81

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent anti-apoptotic Bcl-xL protein inhibitor and apoptosis-inducing agent

MDL Number: N/A

PubChem CID: 71565985

SMILES: CC1=C(C=NN1CC23CC4CC(C2)CC(C4)C3)C5=C(N=C(C=C5)N6CCC7=CC=CC(=C7C6)C(=O)NC8=NC9=CC=CC=C9S8)C(=O)O

InChi: InChI=1S/C38H38N6O3S/c1-22-29(19-39-44(22)21-38-16-23-13-24(17-38)15-25(14-23)18-38)27-9-10-33(41-34(27)36(46)47)43-12-11-26-5-4-6-28(30(26)20-43)35(45)42-37-40-31-7-2-3-8-32(31)48-37/h2-10,19,23-25H,11-18,20-21H2,1H3,(H,46,47)(H,40,42,45)

InChi Key: QCQQONWEDCOTBV-UHFFFAOYSA-N