A-769662 | 1719

Cell-permeable. A potent AMPK activator. Directly stimulates partially purified rat liver AMPK (EC₅₀ = 0.8 µM) and inhibits fatty acid synthesis in primary rat hepatocytes (IC5₅₀ = 3.2 µM).

A-769662 is a potent AMPK activator. Directly stimulates partially purified rat liver AMPK (EC₅₀ = 0.8 µM) and inhibits fatty acid synthesis in primary rat hepatocytes (IC5₅₀ = 3.2 µM).

1719 | A-769662 DataSheet

Alternate Name/Synonyms: 4-Hydroxy-3-(2’-hydroxy-[1,1’-biphenyl]-4-yl-)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 844499-71-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₁₂N₂O₃S

Molecular Weight: 360.39

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO(30 mg/ml) or Ethanol (5 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent AMPK activator

MDL Number: MFCD11977269

PubChem CID: 54708532

SMILES: C1=CC=C(C(=C1)C2=CC=C(C=C2)C3=CSC4=C3C(=C(C(=O)N4)C#N)O)O

InChi: InChI=1S/C20H12N2O3S/c21-9-14-18(24)17-15(10-26-20(17)22-19(14)25)12-7-5-11(6-8-12)13-3-1-2-4-16(13)23/h1-8,10,23H,(H2,22,24,25)

InChi Key: CTESJDQKVOEUOY-UHFFFAOYSA-N