A-966492 | B2174

A-966492 is a potent PARP (poly (ADP-ribose) polymerase) inhibitor that displays potency against the PARP-1 enzyme with a K(i) of 1 nM and an EC₅₀ of 1 nM in a whole cell assay.

A-966492 is a potent PARP (poly (ADP-ribose) polymerase) inhibitor that displays potency against the PARP-1 enzyme with a K(i) of 1 nM and an EC₅₀ of 1 nM in a whole cell assay.

B2174 | A-966492 DataSheet

Alternate Name/Synonyms: 2-[2-Fluoro-4-[(2S)-2-pyrrolidinyl]phenyl]-1H-benzimidazole-7-carboxamide

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 934162-61-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₁₇FN₄O

Molecular Weight: 324.4

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent PARP-1 inhibitor

MDL Number: N/A

PubChem CID: 16666333

SMILES: C1CC(NC1)C2=CC(=C(C=C2)C3=NC4=C(C=CC=C4N3)C(=O)N)F

InChi: InChI=1S/C18H17FN4O/c19-13-9-10(14-5-2-8-21-14)6-7-11(13

InChi Key: AHIVQGOUBLVTCB-AWEZNQCLSA-N